KDM6A promotes hepatocellular carcinoma progression and dictates lenvatinib efficacy by upregulating FGFR4 expression

Abstract Background Hepatocellular carcinoma (HCC) is one of the major causes of death from cancer and has a very poor prognosis with few effective therapeutic options. Despite the approval of lenvatinib for the treatment of patients suffering from advanced HCC, only a small number of patients can b...

Full description

Bibliographic Details
Main Authors: Wenyun Guo, Songling Li, Yifei Qian, Linfeng Li, Fan Wang, Yu Tong, Qianyu Li, Zijun Zhu, Wei‐Qiang Gao, Yanfeng Liu
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1452