PRODUCTION OF ANTI-CD19 CAR T CELLS USING DNA-LOADED IONIZABLE LIPID NANOPARTICLES
Introduction: CAR T cell immunotherapy represents a major breakthrough in treatment of hematological tumors. Its manufacture is based on the ex vivo manipulation of human lymphocytes, which are later reinfused to the patient. New methodologies for the generation of CAR T cells are needed, with a foc...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137923011185 |