pH-dependent structural diversity of profilin allergens determines thermal stability

The family of profilin allergens is a common class of proteins found in plants, viruses and various eukaryotes including mammals. Profilins are characterized by an evolutionary conserved structural fold, which is responsible for their cross-reactive nature of Immunoglobulin E (IgE) antibodies. Despi...

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Bibliographic Details
Main Authors: Florian Hofer, Anna-Lena Fischer, Anna S. Kamenik, Franz Waibl, Monica L. Fernández-Quintero, Klaus R. Liedl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Allergy
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2022.1007000/full