The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia

The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia

Abstract Background RNA sequencing (RNA-seq) has become an indispensable tool to identify disease associated transcriptional profiles and determine the molecular underpinnings of diseases. However, the broad adaptation of the methodology into the clinic is still hampered by inconsistent results from...

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Bibliographic Details
Main Authors: Ashwini Kumar, Matti Kankainen, Alun Parsons, Olli Kallioniemi, Pirkko Mattila, Caroline A. Heckman
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Genomics
Subjects:
RNA-sequencing
Hematological malignancies
Library preparation
Ribo-depletion
Poly-A selection
Online Access:http://link.springer.com/article/10.1186/s12864-017-4039-1

Internet

http://link.springer.com/article/10.1186/s12864-017-4039-1

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