Alpha-7 nicotinic acetylcholine receptor agonist alleviates psoriasis-like inflammation through inhibition of the STAT3 and NF-κB signaling pathway

Alpha-7 nicotinic acetylcholine receptor agonist alleviates psoriasis-like inflammation through inhibition of the STAT3 and NF-κB signaling pathway

Abstract Psoriasis is a chronic inflammatory cutaneous disease; it has been discovered that stimulation of the nervous system increases susceptibility to psoriasis. Although the cholinergic anti-inflammatory pathway, which is mediated by the alpha-7 nicotinic acetylcholine receptor (α7nAChR), is cri...

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Bibliographic Details
Main Authors: Yiwen Chen, Panpan Lian, Ziqi Peng, Junaid Wazir, Chujun Ma, Lulu Wei, Li Li, Jun Liu, Chen Zhao, Wenyuan Pu, Hongwei Wang, Zhonglan Su
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00943-4

Internet

https://doi.org/10.1038/s41420-022-00943-4

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