Cerebellar synapse properties and cerebellum-dependent motor and non-motor performance in Dp71-null mice

Cerebellar synapse properties and cerebellum-dependent motor and non-motor performance in Dp71-null mice

Recent emphasis has been placed on the role that cerebellar dysfunctions could have in the genesis of cognitive deficits in Duchenne muscular dystrophy (DMD). However, relevant genotype-phenotype analyses are missing to define whether cerebellar defects underlie the severe cases of intellectual defi...

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Bibliographic Details
Main Authors: Romain Helleringer, Delphine Le Verger, Xia Li, Charlotte Izabelle, Rémi Chaussenot, Mehdi Belmaati-Cherkaoui, Raoudha Dammak, Paulette Decottignies, Hervé Daniel, Micaela Galante, Cyrille Vaillend
Format: Article
Language:English
Published: The Company of Biologists 2018-07-01
Series:Disease Models & Mechanisms
Subjects:
Dystrophin
Dp71
Purkinje neuron
Glutamatergic transmission
Motor coordination
Cerebellum
Cognitive deficit
Brain
Online Access:http://dmm.biologists.org/content/11/7/dmm033258

Internet

http://dmm.biologists.org/content/11/7/dmm033258

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