Thymoquinone Prevents Dopaminergic Neurodegeneration by Attenuating Oxidative Stress Via the Nrf2/ARE Pathway

Thymoquinone Prevents Dopaminergic Neurodegeneration by Attenuating Oxidative Stress Via the Nrf2/ARE Pathway

Studies have indicated that oxidative stress plays a crucial role in the development of Parkinson’s disease (PD) and other neurodegenerative conditions. Research has also revealed that nuclear factor erythroid 2-related factor 2 (Nrf2) triggers the expression of antioxidant genes via a series of ant...

Full description

Bibliographic Details
Main Authors: Jianjian Dong, Xiaoming Zhang, Shijing Wang, Chenchen Xu, Manli Gao, Songyang Liu, Xiaoxiao Li, Nan Cheng, Yongsheng Han, Xun Wang, Yongzhu Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Parkinson’ s disease
thymoquinone
Nrf2/ARE signaling pathway
oxidative stress
neurodegeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.615598/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.615598/full

Similar Items