Activation of a Vibrio cholerae CBASS anti-phage system by quorum sensing and folate depletion

Activation of a Vibrio cholerae CBASS anti-phage system by quorum sensing and folate depletion

ABSTRACT A major challenge faced by bacteria is infection by bacteriophage (phage). Abortive infection is one strategy for combating phage in which an infected cell kills itself to limit phage replication, thus protecting neighboring kin. One class of abortive infection systems is the cyclic oligonu...

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Bibliographic Details
Main Authors: Geoffrey B. Severin, Miriam S. Ramliden, Kathryne C. Ford, Andrew J. Van Alst, Ram Sanath-Kumar, Kaitlin A. Decker, Brian Y. Hsueh, Gong Chen, Soo Hun Yoon, Lucas M. Demey, Brendan J. O'Hara, Christopher R. Rhoades, Victor J. DiRita, Wai-Leung Ng, Christopher M. Waters
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
cyclic GMP-AMP
CD-NTases
phage
quorum sensing
folate
Online Access:https://journals.asm.org/doi/10.1128/mbio.00875-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00875-23

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