A phylogenetic approach to inferring the order in which mutations arise during cancer progression.

Although the role of evolutionary process in cancer progression is widely accepted, increasing attention is being given to the evolutionary mechanisms that can lead to differences in clinical outcome. Recent studies suggest that the temporal order in which somatic mutations accumulate during cancer...

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Bibliographic Details
Main Authors: Yuan Gao, Jeff Gaither, Julia Chifman, Laura Kubatko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010560