Of Seven New K<sup>+</sup> Channel Inhibitor Peptides of <i>Centruroides bonito</i>, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Of Seven New K<sup>+</sup> Channel Inhibitor Peptides of <i>Centruroides bonito</i>, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Seven new peptides denominated CboK1 to CboK7 were isolated from the venom of the Mexican scorpion <i>Centruroides bonito</i> and their primary structures were determined. The molecular weights ranged between 3760.4 Da and 4357.9 Da, containing 32 to 39 amino acid residues with three put...

Full description

Bibliographic Details
Main Authors: Kashmala Shakeel, Timoteo Olamendi-Portugal, Muhammad Umair Naseem, Baltazar Becerril, Fernando Z. Zamudio, Gustavo Delgado-Prudencio, Lourival Domingos Possani, Gyorgy Panyi
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Toxins
Subjects:
CboK
scorpion toxin
<i>Centruroides bonito</i>
Kv1.2
Kv1.3
Kv1.2 channelopathies
Online Access:https://www.mdpi.com/2072-6651/15/8/506

Internet

https://www.mdpi.com/2072-6651/15/8/506

Similar Items