Of Seven New K<sup>+</sup> Channel Inhibitor Peptides of <i>Centruroides bonito</i>, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Of Seven New K<sup>+</sup> Channel Inhibitor Peptides of <i>Centruroides bonito</i>, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Seven new peptides denominated CboK1 to CboK7 were isolated from the venom of the Mexican scorpion <i>Centruroides bonito</i> and their primary structures were determined. The molecular weights ranged between 3760.4 Da and 4357.9 Da, containing 32 to 39 amino acid residues with three put...

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Bibliographic Details
Main Authors: Kashmala Shakeel, Timoteo Olamendi-Portugal, Muhammad Umair Naseem, Baltazar Becerril, Fernando Z. Zamudio, Gustavo Delgado-Prudencio, Lourival Domingos Possani, Gyorgy Panyi
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Toxins
Subjects:
CboK
scorpion toxin
<i>Centruroides bonito</i>
Kv1.2
Kv1.3
Kv1.2 channelopathies
Online Access:https://www.mdpi.com/2072-6651/15/8/506

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