Radiation-induced gastrointestinal (GI) syndrome as a function of age

Abstract Previous studies show increased sensitivity of older mice (28–29 months) compared with young adult mice (3 months, possessing a mature immune system) to radiation-induced GI lethality. Age-dependent lethality was associated with higher levels of apoptotic stem cells in small intestinal cryp...

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Bibliographic Details
Main Authors: Hongyan Li, Herman C. Kucharavy, Carla Hajj, Liyang Zhao, Guoqiang Hua, Ryan Glass, Phillip B. Paty, Zvi Fuks, Richard Kolesnick, Karen Hubbard, Adriana Haimovitz-Friedman
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01298-0