ΔNp63α promotes Epstein-Barr virus latency in undifferentiated epithelial cells.

Epstein-Barr virus (EBV) is a human herpesvirus that causes infectious mononucleosis and contributes to both B-cell and epithelial-cell malignancies. EBV-infected epithelial cell tumors, including nasopharyngeal carcinoma (NPC), are largely composed of latently infected cells, but the mechanism(s) m...

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Bibliographic Details
Main Authors: Nicholas Van Sciver, Makoto Ohashi, Dhananjay M Nawandar, Nicholas P Pauly, Denis Lee, Kathleen R Makielski, Jillian A Bristol, Sai Wah Tsao, Paul F Lambert, Eric C Johannsen, Shannon C Kenney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010045