Pathogenicity of Mycobacterium tuberculosis is expressed by regulating metabolic thresholds of the host macrophage.

The success of Mycobacterium tuberculosis as a pathogen derives from its facile adaptation to the intracellular milieu of human macrophages. To explore this process, we asked whether adaptation also required interference with the metabolic machinery of the host cell. Temporal profiling of the metabo...

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Bibliographic Details
Main Authors: Parul Mehrotra, Shilpa V Jamwal, Najmuddin Saquib, Neeraj Sinha, Zaved Siddiqui, Venkatasamy Manivel, Samrat Chatterjee, Kanury V S Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4110042?pdf=render