A four-stage model for murine natural killer cell development in vivo

Abstract Natural killer (NK) cells are the predominant innate lymphoid cells that mediate anti-viral and anti-tumor immunity. NK cells arise from hematopoietic stem cells in the bone marrow (BM) and undergo lineage specification and maturation. Despite the importance of NK cells for innate immunity...

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Bibliographic Details
Main Authors: Shoubao Ma, Michael A. Caligiuri, Jianhua Yu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-022-01243-1