A four-stage model for murine natural killer cell development in vivo
Abstract Natural killer (NK) cells are the predominant innate lymphoid cells that mediate anti-viral and anti-tumor immunity. NK cells arise from hematopoietic stem cells in the bone marrow (BM) and undergo lineage specification and maturation. Despite the importance of NK cells for innate immunity...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-03-01
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Series: | Journal of Hematology & Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13045-022-01243-1 |