Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population

Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population

BackgroundSudden unexplained nocturnal death syndrome (SUNDS) remains an autopsy negative entity with unclear etiology. Arrhythmia has been implicated in SUNDS. Mutations/deficiencies in intercalated disc components have been shown to cause arrhythmias. Human cardiomyopathy‐associated 1 (XIRP1) and...

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Bibliographic Details
Main Authors: Lei Huang, Kuo‐Ho Wu, Liyong Zhang, Qinchuan Wang, Shuangbo Tang, Qiuping Wu, Pei‐Hsiu Jiang, Jim Jung‐Ching Lin, Jian Guo, Lin Wang, Shih‐Hurng Loh, Jianding Cheng
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Xirp proteins
cardiac conduction
rare variants
sudden cardiac death
sudden unexplained nocturnal death syndrome
Brugada syndrome
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.006320

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.006320

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