Early Age of Onset Is an Independent Predictor for a Worse Response to Neoadjuvant Therapies in Sporadic Rectal Cancer Patients

Early Age of Onset Is an Independent Predictor for a Worse Response to Neoadjuvant Therapies in Sporadic Rectal Cancer Patients

The incidence of rectal cancer (RC) is increasing in the population aged ≤ 49 (early-onset RC-EORC). EORC patients are more likely to present with locally advanced disease at diagnosis than late-onset RC (LORC; aged ≥ 50) patients. As a consequence, more EORC patients undergo neoadjuvant therapies....

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Bibliographic Details
Main Authors: Caterina Foppa, Annalisa Maroli, Antonio Luberto, Carlotta La Raja, Paola Spaggiari, Cristiana Bonifacio, Stefano De Zanet, Marco Montorsi, Salvatore Piscuoglio, Luigi Maria Terracciano, Armando Santoro, Antonino Spinelli
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
early-onset
rectal cancer
late-onset
neoadjuvant therapies
age of onset
tumor regression grade
Online Access:https://www.mdpi.com/2072-6694/15/14/3750

Internet

https://www.mdpi.com/2072-6694/15/14/3750

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