SIRT2, ERK and Nrf2 Mediate NAD+ Treatment-Induced Increase in the Antioxidant Capacity of PC12 Cells Under Basal Conditions

NAD+ (oxidized form of nicotinamide adenine dinucleotide) administration is highly beneficial in numerous models of diseases and aging. It is becoming increasingly important to determine if NAD+ treatment may directly increase the antioxidant capacity of cells under basal conditions. In the current...

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Bibliographic Details
Main Authors: Jie Zhang, Yunyi Hong, Wei Cao, Shankai Yin, Haibo Shi, Weihai Ying
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00108/full