The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an <em>in vitro</em> model of benign steatosis

The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an <em>in vitro</em> model of benign steatosis

It has been previously found that the blockade of metabotropic glutamate receptor type 5 (mGluR5) protects against hepatic ischemia/reperfusion injury and acetaminophen toxicity. The role of mGluR5 in NAFLD has not yet been elucidated. Here, we evaluated the effects of mGluR5 blockade in an in vitro...

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Bibliographic Details
Main Authors: Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti
Format: Article
Language:English
Published: PAGEPress Publications 2020-11-01
Series:European Journal of Histochemistry
Subjects:
NAFLD
mGluR5
MPEP
oleate/palmitate
HepG2
SREBP-1
Online Access:https://ejh.it/index.php/ejh/article/view/3175

Internet

https://ejh.it/index.php/ejh/article/view/3175

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