Facile Synthesis of Functionalized Phenoxy Quinolines: Antibacterial Activities against ESBL Producing <i>Escherichia coli</i> and MRSA, Docking Studies, and Structural Features Determination through Computational Approach

Facile Synthesis of Functionalized Phenoxy Quinolines: Antibacterial Activities against ESBL Producing <i>Escherichia coli</i> and MRSA, Docking Studies, and Structural Features Determination through Computational Approach

The synthesis of new 6-Bromoquinolin-4-ol derivatives (<b>3a</b>–<b>3h</b>) by Chan–Lam coupling utilizing different types of solvents (protic, aprotic, and mixed solvents) and bases was studied in the present manuscript. Furthermore, their potential against ESBL producing &l...

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Bibliographic Details
Main Authors: Mahwish Arshad, Nasir Rasool, Muhammad Usman Qamar, Syed Adnan Ali Shah, Zainul Amiruddin Zakaria
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
4-methyl phenylboronic acid
Chan–Lam coupling
antibacterial activity
molecular docking
NLO properties
<sup>1</sup>H NMR comparison
Online Access:https://www.mdpi.com/1420-3049/27/12/3732

Internet

https://www.mdpi.com/1420-3049/27/12/3732

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