Hand2 inhibits kidney specification while promoting vein formation within the posterior mesoderm

Hand2 inhibits kidney specification while promoting vein formation within the posterior mesoderm

Proper organogenesis depends upon defining the precise dimensions of organ progenitor territories. Kidney progenitors originate within the intermediate mesoderm (IM), but the pathways that set the boundaries of the IM are poorly understood. Here, we show that the bHLH transcription factor Hand2 limi...

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Bibliographic Details
Main Authors: Elliot A Perens, Zayra V Garavito-Aguilar, Gina P Guio-Vega, Karen T Peña, Yocheved L Schindler, Deborah Yelon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-11-01
Series:eLife
Subjects:
intermediate mesoderm
pronephron
zebrafish
organogenesis
Hand2
Osr1
Online Access:https://elifesciences.org/articles/19941

Internet

https://elifesciences.org/articles/19941

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