The first non-prion pathogen identified: neurotropic influenza virus

The cellular isoform of prion protein, designated PrPC, is a membrane glycoprotein expressed most abundantly in the brain, particularly by neurons, and its conformational conversion into the abnormally folded, amyloidogenic isoform, PrPSc, is an underlying mechanism in the pathogenesis of prion dise...

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Bibliographic Details
Main Authors: Suehiro Sakaguchi, Hideyuki Hara
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Prion
Subjects:
Online Access:http://dx.doi.org/10.1080/19336896.2021.2015224