Eluxadoline Loaded Solid Lipid Nanoparticles for Improved Colon Targeting in Rat Model of Ulcerative Colitis

The aim of the current study was to evaluate the therapeutics potential of eluxadoline (ELX) loaded solid lipid nanoparticles (SLNs) in ulcerative colitis. ELX loaded SLNs were prepared using three different lipids according to the solvent emulsification technique. The optimization of prepared SLNs...

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Bibliographic Details
Main Authors: Md. Khalid Anwer, Mohammed Muqtader Ahmed, Mohammed F. Aldawsari, Saad Alshahrani, Farhat Fatima, Mohd Nazam Ansari, Najeeb Ur Rehman, Ramadan I. Al-Shdefat
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/9/255