Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway epithelium

Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway epithelium

IntroductionToll-like receptors (TLRs) are an extensive group of proteins involved in host defense processes that express themselves upon the increased production of endogenous damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) due to the constant contact...

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Bibliographic Details
Main Authors: Walter V. Velasco, Nasim Khosravi, Susana Castro-Pando, Nelly Torres-Garza, Maria T. Grimaldo, Avantika Krishna, Michael J. Clowers, Misha Umer, Sabah Tariq Amir, Diana Del Bosque, Soudabeh Daliri, Maria Miguelina De La Garza, Marco Ramos-Castaneda, Scott E. Evans, Seyed Javad Moghaddam
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
COPD
KRAS
toll-like receptor
lung cancer
IKK beta
MyD88
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1118721/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1118721/full

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