Methionine Restriction Improves Cognitive Ability by Alleviating Hippocampal Neuronal Apoptosis through H19 in Middle-Aged Insulin-Resistant Mice

Methionine Restriction Improves Cognitive Ability by Alleviating Hippocampal Neuronal Apoptosis through H19 in Middle-Aged Insulin-Resistant Mice

LncRNA H19 has been reported to regulate apoptosis and neurological diseases. Hippocampal neuron apoptosis damages cognitive ability. Methionine restriction (MR) can improve cognitive impairment. However, the effect of MR on hippocampal neuronal apoptosis induced by a high-fat diet (HFD) in middle-a...

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Bibliographic Details
Main Authors: Chuanxing Feng, Yuge Jiang, Shiying Li, Yueting Ge, Yonghui Shi, Xue Tang, Guowei Le
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Nutrients
Subjects:
methionine restriction
neuron apoptosis
cognitive ability
insulin resistance
oxidative stress
Online Access:https://www.mdpi.com/2072-6643/14/21/4503

Internet

https://www.mdpi.com/2072-6643/14/21/4503

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