Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes

<p>Abstract</p> <p>Background</p> <p>It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has been intensively studied in type 1 diabetes, but not in human type 2 diabetes....

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Bibliographic Details
Main Authors: Yoon Kun-Ho, Wang-Rodriguez Jessica, Dib Sergio A, Anachkov Kamen A, Tyrberg Björn, Levine Fred
Format: Article
Language:English
Published: BMC 2002-04-01
Series:BMC Endocrine Disorders
Online Access:http://www.biomedcentral.com/1472-6823/2/2