In silico validation of RNA-Seq results can identify gene fusions with oncogenic potential in glioblastoma

In silico validation of RNA-Seq results can identify gene fusions with oncogenic potential in glioblastoma

Abstract RNA-Sequencing (RNA-Seq) can identify gene fusions in tumors, but not all these fusions have functional consequences. Using multiple data bases, we have performed an in silico analysis of fusions detected by RNA-Seq in tumor samples from 139 newly diagnosed glioblastoma patients to identify...

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Bibliographic Details
Main Authors: Ainhoa Hernandez, Ana Maria Muñoz-Mármol, Anna Esteve-Codina, Francesc Alameda, Cristina Carrato, Estela Pineda, Oriol Arpí-Lluciá, Maria Martinez-García, Mar Mallo, Marta Gut, Sonia del Barco, Oscar Gallego, Marc Dabad, Carlos Mesia, Beatriz Bellosillo, Marta Domenech, Noemí Vidal, Iban Aldecoa, Nuria de la Iglesia, Carmen Balana
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18608-8

Internet

https://doi.org/10.1038/s41598-022-18608-8

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