Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice.

Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice.

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive deterioration of cognitive functions, extracellular β-amyloid (Aβ) plaques and intracellular neurofibrillary tangles within neocortex and hippocampus. Adult hippocampal neurogenesis plays an import...

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Bibliographic Details
Main Authors: Anna Fiorentini, Maria Cristina Rosi, Cristina Grossi, Ilaria Luccarini, Fiorella Casamenti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3004858?pdf=render

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http://europepmc.org/articles/PMC3004858?pdf=render

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