ADMET profiling and molecular docking of pyrazole and pyrazolines derivatives as antimicrobial agents

ADMET profiling and molecular docking of pyrazole and pyrazolines derivatives as antimicrobial agents

In the present study, a Molecular Docking and in silico ADMET analysis were performed to identify the possible inhibitory effect of 23 molecules, pyrazole and pyrazolines derivatives, on Escherichia coli and to predict the absorption, distribution, metabolism, excretion, and toxicity (ADMET) propert...

全面介紹

書目詳細資料
Main Authors: Fatima EN-NAHLI, Halima HAJJI, Mohamed OUABANE, Mohammed Aziz AJANA, Chakib SEKATTE, Tahar LAKHLIFI, Mohammed BOUACHRINE
格式: Article
語言:English
出版: Elsevier 2023-11-01
叢編:Arabian Journal of Chemistry
主題:
ADMET
Escherichia coli
Molecular Docking
Lipinski’s rule
Pyrazole and pyrazolines derivatives
在線閱讀:http://www.sciencedirect.com/science/article/pii/S1878535223007244

因特網

http://www.sciencedirect.com/science/article/pii/S1878535223007244

相似書籍