Clinical use of CCR5 inhibitors in HIV and beyond

<p>Abstract</p> <p>Since the discovery of CCR5 as a coreceptor for HIV entry, there has been interest in blockade of the receptor for treatment and prevention of HIV infection. Although several CCR5 antagonists have been evaluated in clinical trials, only maraviroc has been approve...

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Bibliographic Details
Main Authors: Gilliam Bruce, Riedel David, Redfield Robert
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/S1/S9