Right ventricular myocardial oxygen tension is reduced in monocrotaline-induced pulmonary hypertension in the rat and restored by myo-inositol trispyrophosphate

Right ventricular myocardial oxygen tension is reduced in monocrotaline-induced pulmonary hypertension in the rat and restored by myo-inositol trispyrophosphate

Abstract Pulmonary hypertension (PH) initially results in compensatory right ventricular (RV) hypertrophy, but eventually in RV failure. This transition is poorly understood, but may be triggered by hypoxia. Measurements of RV oxygen tension (pO2) in PH are lacking. We hypothesized that RV hypoxia o...

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Bibliographic Details
Main Authors: Marta Oknińska, Zuzanna Zambrowska, Karolina Zajda, Aleksandra Paterek, Klaudia Brodaczewska, Urszula Mackiewicz, Cezary Szczylik, Adam Torbicki, Claudine Kieda, Michał Mączewski
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97470-6

Internet

https://doi.org/10.1038/s41598-021-97470-6

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