Neutralization of LINGO-1 during in vitro differentiation of neural stem cells results in proliferation of immature neurons.

Identifying external factors that can be used to control neural stem cells division and their differentiation to neurons, astrocytes and oligodendrocytes is of high scientific and clinical interest. Here we show that the Nogo-66 receptor interacting protein LINGO-1 is a potent regulator of neural st...

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Bibliographic Details
Main Authors: Camilla Lööv, Maria Fernqvist, Adrian Walmsley, Niklas Marklund, Anna Erlandsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3250485?pdf=render