Preparation of pellets containing highly soluble drug by extrusion/spheronisation and coating with Kollicoat® SR 30D

The aim of this study was to prepare and evaluate the pellets, containing a highly soluble drug (ascorbic acid), by the extrusion-spheronization process and coated with a release controlling polymer. The coating (undertaken in a fluid bed) was applied to three batches of the pellets with a dispersio...

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Bibliographic Details
Main Authors: Itamar Francisco Andreazza, Humberto Gomes Ferraz
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2011-04-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000200013