Adenosine/adenosine type 1 receptor signaling pathway did not play dominant roles on the influence of sodium–glucose cotransporter 2 inhibitor in the kidney of bovine serum albumin‐overloaded streptozotocin‐induced diabetic mice

Adenosine/adenosine type 1 receptor signaling pathway did not play dominant roles on the influence of sodium–glucose cotransporter 2 inhibitor in the kidney of bovine serum albumin‐overloaded streptozotocin‐induced diabetic mice

Abstract Aims/Introduction Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have been shown to display excellent renoprotective effects in diabetic kidney disease with macroalbuminuria/proteinuria. Regarding the renoprotective mechanism of SGLT2i, a sophisticated hypothesis was made by explaining...

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Bibliographic Details
Main Authors: Keiji Shimada, Keizo Kanasaki, Makoto Kato, Yoshio Ogura, Yuta Takagaki, Itaru Monno, Taro Hirai, Munehiro Kitada, Daisuke Koya
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Journal of Diabetes Investigation
Subjects:
Adenosine A1 receptor inhibitor
Glomerular hyperfiltration
Sodium–glucose cotransporter 2 inhibitor
Online Access:https://doi.org/10.1111/jdi.13760

Internet

https://doi.org/10.1111/jdi.13760

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