High-performance method for identification of super enhancers from ChIP-Seq data with configurable cloud virtual machines

A universal method for rapid identifying super-enhancers which are large domains of multiple closely-spaced enhancers is proposed. The method applies configurable cloud virtual machines (cVMs) and the rank-ordering of super-enhancers (ROSE) algorithm. To identify super-enhancers a сVM-based analysis...

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Bibliographic Details
Main Authors: Natalia N. Orlova, Olga V. Bogatova, Alexey V. Orlov
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221501612030385X