Purkinje cell dopaminergic inputs to astrocytes regulate cerebellar-dependent behavior

The role of dopamine in the cerebellum remains relatively unexplored. Here, the authors report a dopamine system in the cerebellum in mice, where Purkinje cells supply dopamine and Bergmann glia express D1 receptors. Activation of D1 receptors is found to modulate Purkinje cell activity and to affec...

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Bibliographic Details
Main Authors: Chang Li, Natalie B. Saliba, Hannah Martin, Nicole A. Losurdo, Kian Kolahdouzan, Riyan Siddiqui, Destynie Medeiros, Wei Li
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37319-w