The role of epithelial-mesenchymal transition and autophagy in pancreatic ductal adenocarcinoma invasion

Abstract Of all pancreatic cancer (PC) cases, approximately 90% are pancreatic ductal adenocarcinoma (PDAC), which progress rapidly due to its high degree of invasiveness and high metastatic potential. Epithelial-mesenchymal transition (EMT) is a prerequisite for cancer cell invasion and spread, and...

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Bibliographic Details
Main Authors: Jian Yang, Ying Liu, Shi Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06032-3