SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion

Abstract Macroautophagy/autophagy is an evolutionarily conserved and tightly regulated catabolic process involved in the maintenance of cellular homeostasis whose dysregulation is implicated in several pathological processes. Autophagy begins with the formation of phagophores that engulf cytoplasmic...

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Bibliographic Details
Main Authors: Patricia González-Rodríguez, Elizabeth Delorme-Axford, Amélie Bernard, Lily Keane, Vassilis Stratoulias, Kathleen Grabert, Pinelopi Engskog-Vlachos, Jens Füllgrabe, Daniel J. Klionsky, Bertrand Joseph
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05381-9