SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion
Abstract Macroautophagy/autophagy is an evolutionarily conserved and tightly regulated catabolic process involved in the maintenance of cellular homeostasis whose dysregulation is implicated in several pathological processes. Autophagy begins with the formation of phagophores that engulf cytoplasmic...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-11-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05381-9 |