The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness

The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness

Abstract Background The Ghrelin-system is a complex, pleiotropic family composed of several peptides, including native-ghrelin and its In1-ghrelin splicing variant, and receptors (GHSR 1a/b), which are dysregulated in various endocrine-related tumors, where they associate to pathophysiological featu...

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Main Authors: Daniel Hormaechea-Agulla, Manuel D. Gahete, Juan M. Jiménez-Vacas, Enrique Gómez-Gómez, Alejandro Ibáñez-Costa, Fernando L-López, Esther Rivero-Cortés, André Sarmento-Cabral, José Valero-Rosa, Julia Carrasco-Valiente, Rafael Sánchez-Sánchez, Rosa Ortega-Salas, María M. Moreno, Natia Tsomaia, Steve M. Swanson, Michael D. Culler, María J. Requena, Justo P. Castaño, Raúl M. Luque
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Molecular Cancer
Subjects:
Ghrelin-system
In1-ghrelin variant
Prostate cancer
Aggressiveness
Online Access:http://link.springer.com/article/10.1186/s12943-017-0713-9

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http://link.springer.com/article/10.1186/s12943-017-0713-9

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