Deciphering the potential role of post-translational modifications of histones in gastrointestinal cancers: a proteomics-based review with therapeutic challenges and opportunities

Oncogenesis is a complex and multi-step process, controlled by several factors including epigenetic modifications. It is considered that histone modifications are critical components in the regulation of gene expression, protein functions, and molecular interactions. Dysregulated post-translationall...

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Autors principals: Reyhaneh Farrokhi Yekta, Masoumeh Farahani, Mehdi Koushki, Nasrin Amiri-Dashatan
Format: Article
Idioma:English
Publicat: Frontiers Media S.A. 2024-10-01
Col·lecció:Frontiers in Oncology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fonc.2024.1481426/full