Significance of TP53 mutation in bladder cancer disease progression and drug selection

Significance of TP53 mutation in bladder cancer disease progression and drug selection

Background The tumor protein p53 (TP53) mutant is one of the most frequent mutant genes in bladder cancer. In this study, we assessed the importance of the TP53 mutation in bladder cancer progression and drug selection, and identified potential pathways and core genes associated with the underlying...

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Bibliographic Details
Main Authors: Guang Wu, Fei Wang, Kai Li, Shugen Li, Chunchun Zhao, Caibin Fan, Jianqing Wang
Format: Article
Language:English
Published: PeerJ Inc. 2019-12-01
Series:PeerJ
Subjects:
Bladder cancer
TP53 mutation
TCGA
RNA sequencing
Bioinformatics analysis
Drug selection
Online Access:https://peerj.com/articles/8261.pdf

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https://peerj.com/articles/8261.pdf

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