Monitoring the in vivo siRNA release from lipid nanoparticles based on the fluorescence resonance energy transfer principle

Monitoring the in vivo siRNA release from lipid nanoparticles based on the fluorescence resonance energy transfer principle

The siRNA-loaded lipid nanoparticles have attracted much attention due to its significant gene silencing effect and successful marketization. However, the in vivo distribution and release of siRNA still cannot be effectively monitored. In this study, based on the fluorescence resonance energy transf...

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Bibliographic Details
Main Authors: Lei Sun, Jinfang Zhang, Jing-e Zhou, Jing Wang, Zhehao Wang, Shenggen Luo, Yeying Wang, Shulei Zhu, Fan Yang, Jie Tang, Wei Lu, Yiting Wang, Lei Yu, Zhiqiang Yan
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Survivin siRNA
Lipid nanoparticles
In vivo release
Nanogolds
Fluorescence resonance energy transfer
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087622001180

Internet

http://www.sciencedirect.com/science/article/pii/S1818087622001180

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