Somite Division and New Boundary Formation by Mechanical Strain

Summary: Somitogenesis, the primary segmentation of the vertebrate embryo, is associated with oscillating genes that interact with a wave of cell differentiation. The necessity of cell-matrix adherence and embryonic tension, however, suggests that mechanical cues are also involved. To explicitly inv...

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Bibliographic Details
Main Authors: Ben K.A. Nelemans, Manuel Schmitz, Hannan Tahir, Roeland M.H. Merks, Theodoor H. Smit
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301607