Antipsychotic- and Anxiolytic-like Properties of a Multimodal Compound JJGW08 in Rodents

Antipsychotic- and Anxiolytic-like Properties of a Multimodal Compound JJGW08 in Rodents

Schizophrenia is a chronic mental illness, which remains difficult to treat. A high resistance to the available therapies, their insufficient efficacy, and numerous side effects are the reasons why there is an urgent need to develop new antipsychotics. This study aimed to assess the antipsychotic-li...

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Bibliographic Details
Main Authors: Elżbieta Żmudzka, Klaudia Lustyk, Monika Głuch-Lutwin, Barbara Mordyl, Alicja Zakrzewska-Sito, Paweł Mierzejewski, Jolanta Jaśkowska, Marcin Kołaczkowski, Jacek Sapa, Karolina Pytka
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
antipsychotic-like activity
anxiolytic-like effect
D<sub>2</sub> receptor antagonist
5-HT<sub>1A</sub> receptor antagonist
arylpiperazine derivative of salicylamide
Online Access:https://www.mdpi.com/1422-0067/23/24/15929

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https://www.mdpi.com/1422-0067/23/24/15929

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