Dysfunction of Human Estrogen Signaling as a Novel Molecular Signature of Polycystic Ovary Syndrome

Dysfunction of Human Estrogen Signaling as a Novel Molecular Signature of Polycystic Ovary Syndrome

Estradiol (E2) is a major hormone-controlling folliculogenesis whose dysfunction may participate in polycystic ovary syndrome (PCOS) infertility. To determine whether both the concentration and action of E2 could be impaired in non-hyperandrogenic overweight PCOS women, we isolated granulosa cells (...

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Bibliographic Details
Main Authors: Clémentine Marie, Alice Pierre, Anne Mayeur, Frank Giton, Raphael Corre, Michaël Grynberg, Joëlle Cohen-Tannoudji, Céline J. Guigon, Stéphanie Chauvin
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
granulosa cells
polycystic ovary syndrome
17β-estradiol
steroids
follicular fluid
Online Access:https://www.mdpi.com/1422-0067/24/23/16689

Internet

https://www.mdpi.com/1422-0067/24/23/16689

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