Whole inactivated dengue virus-loaded trimethyl chitosan nanoparticle-based vaccine: immunogenic properties in ex vivo and in vivo models

Whole inactivated dengue virus-loaded trimethyl chitosan nanoparticle-based vaccine: immunogenic properties in ex vivo and in vivo models

Dengue virus (DENV) is a mosquito-borne virus that poses an incomparable public health problem, particularly in tropical and subtropical areas. Vaccination remains the most rational measure for controlling DENV infection. In this study, an ultraviolet irradiation (UV)-inactivated DENV-2 carried by N...

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Bibliographic Details
Main Authors: Tuksin Jearanaiwitayakul, Panya Sunintaboon, Runglawan Chawengkittikul, Jitra Limthongkul, Panuwat Midoeng, Preamrudee Chaisuwirat, Saradee warit, Sukathida Ubol
Format: Article
Language:English
Published: Taylor & Francis Group 2021-08-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
dengue nanovaccine
whole inactivated dengue virus
adjuvant-delivery nanoparticle
trimethyl chitosan nanoparticles
immunogenicity
Online Access:http://dx.doi.org/10.1080/21645515.2021.1884473

Internet

http://dx.doi.org/10.1080/21645515.2021.1884473

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