SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease worldwide. In 20-30% of patients, NAFLD can progress into non-alcoholic steatohepatitis (NASH), eventually leading to fibrosis, cirrhosis and hepatocellular carcinoma development. SerpinB3 (SB3), a hypoxia-in...

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Bibliographic Details
Main Authors: Erica Novo, Andrea Cappon, Gianmarco Villano, Santina Quarta, Stefania Cannito, Claudia Bocca, Cristian Turato, Maria Guido, Marina Maggiora, Francesca Protopapa, Salvatore Sutti, Alessia Provera, Mariagrazia Ruvoletto, Alessandra Biasiolo, Beatrice Foglia, Emanuele Albano, Patrizia Pontisso, Maurizio Parola
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
NASH
SerpinB3
macrophages
innate immunity
hepatocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.910526/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.910526/full

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