The effect of semen cuscutae flavonoid on Sertoli cells and blood-testis barrier in male infertility: integrating network pharmacology and experimental verification

The effect of semen cuscutae flavonoid on Sertoli cells and blood-testis barrier in male infertility: integrating network pharmacology and experimental verification

AbstractContext Semen cuscutae is commonly used to treat male infertility (MI), and semen cuscutae flavonoid (SCF) is the main active component of semen cuscutae. The therapeutic mechanism of SCF on MI is still unclear.Objective To clarify the mechanisms of SCF against MI.Materials and methods Netwo...

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Bibliographic Details
Main Authors: Chen-xiao Liu, Su-qin Hu, Dian-long Liu, Ya-hui Xu, Ke Hu, Jian Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Pharmaceutical Biology
Subjects:
Chinese herbal medicinal ingredient
heat stress
molecular docking
PI3K-AKT signaling pathway
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2023.2229380

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2023.2229380

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