Investigation of Experimental and In Silico Physicochemical Propertiesof Thiazole-Pyridinium Anti-Acetylcholinesterase Derivatives withPotential Anti-Alzheimer’s Activity

Investigation of Experimental and In Silico Physicochemical Propertiesof Thiazole-Pyridinium Anti-Acetylcholinesterase Derivatives withPotential Anti-Alzheimer’s Activity

Background: Physicochemical properties play important role in fundamental issues likeabsorption and distribution of pharmaceuticals to the target tissue. This is particularly importantfor drugs acting in central nervous system (CNS). In this study, physicochemical properties ofpreviously synthesized...

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Bibliographic Details
Main Authors: Golaleh Ghotbi, Maryam Hamzeh-Mivehroud, Arezou Taghvimi, Soodabeh Davaran, Siavoush Dastmalchi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2021-09-01
Series:Pharmaceutical Sciences
Subjects:
physicochemical property
partition coefficient
high performance thin layer chromatography
druglikeness
thiazole-pyridinium
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-27-366.pdf

Internet

https://ps.tbzmed.ac.ir/PDF/ps-27-366.pdf

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