Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation.

Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation.

Eph-ephrin system plays a central role in a large variety of human cancers. In fact, alterated expression and/or de-regulated function of Eph-ephrin system promotes tumorigenesis and development of a more aggressive and metastatic tumour phenotype. In particular EphA2 upregulation is correlated with...

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Bibliographic Details
Main Authors: Carmine Giorgio, Iftiin Hassan Mohamed, Lisa Flammini, Elisabetta Barocelli, Matteo Incerti, Alessio Lodola, Massimiliano Tognolini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3068151?pdf=render

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http://europepmc.org/articles/PMC3068151?pdf=render

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